Iran's Supreme Leader Ayatollah Ali Khamenei said on Wednesday blamed western "stubborness" for the ongoing dispute over Iran's nuclear programme.

Khamenei accused the West of being more interested in regime change than ending the dispute, voicing desire to resolve an issue which has led to ever tighter sanctions on Iran's oil sector and the wider economy.

"Some countries have organised a united front against Iran and are misguiding the international community and with stubbornness do not want to see the nuclear issue resolved," Khamenei's official web site quoted him as saying.

"But if they put aside their stubbornness, resolving the nuclear issue would be simple," he added.